Skip to content
Facebook Twitter Linkedin
InMed-logo-01
  • Pharmaceutical
    • Cannabinoids in Development
    • INM-755 for Epidermolysis Bullosa
    • INM-088 for Glaucoma
    • Neurodegenerative Disease
    • Novel Cannabinoid Analogs
  • Manufacturing
    • Cannabinoid Manufacturing Expertise
    • IntegraSyn™ Cannabinoid Manufacturing
    • BayMedica Cannabinoid Biosynthesis
    • Rare Cannabinoid Ingredients
  • Investor
    • News Releases
    • Events
    • Stock Information
    • Corporate Governance
    • Financials & AGM
    • Filings
    • Presentations
    • Media
  • Corporate
    • Management
    • Board of Directors
    • Scientific Advisory Board
    • Partners and Collaborators
    • Events Calendar
    • Careers
    • Contact
  • Learn
    • What is Cannabinol (CBN)?
    • What is Epidermolysis Bullosa (EB)?
    • What is Glaucoma?
    • Cannabinoid Manufacturing Economics 101
    • GMP Manufacturing Standards by Product Type
    • Cannabis Treatments for Glaucoma
    • Cannabinoid Science
    • Articles and Videos
Menu
  • Pharmaceutical
    • Cannabinoids in Development
    • INM-755 for Epidermolysis Bullosa
    • INM-088 for Glaucoma
    • Neurodegenerative Disease
    • Novel Cannabinoid Analogs
  • Manufacturing
    • Cannabinoid Manufacturing Expertise
    • IntegraSyn™ Cannabinoid Manufacturing
    • BayMedica Cannabinoid Biosynthesis
    • Rare Cannabinoid Ingredients
  • Investor
    • News Releases
    • Events
    • Stock Information
    • Corporate Governance
    • Financials & AGM
    • Filings
    • Presentations
    • Media
  • Corporate
    • Management
    • Board of Directors
    • Scientific Advisory Board
    • Partners and Collaborators
    • Events Calendar
    • Careers
    • Contact
  • Learn
    • What is Cannabinol (CBN)?
    • What is Epidermolysis Bullosa (EB)?
    • What is Glaucoma?
    • Cannabinoid Manufacturing Economics 101
    • GMP Manufacturing Standards by Product Type
    • Cannabis Treatments for Glaucoma
    • Cannabinoid Science
    • Articles and Videos
NASDAQ_Logo

Rare Cannabinoid for Neurodegenerative Diseases

InMed has expanded its pharmaceutical pipeline to investigate rare cannabinoids for their potential in treating neurodegenerative diseases such as Alzheimer’s Disease, Parkinson’s Disease, Huntington’s Disease and others.

elderly hands

Early data demonstrates rare cannabinoid potential in treating neurodegenerative disease

InMed has conducted research demonstrating how a specific rare cannabinoid inhibits or slows the progression of neurodegenerative disease. The rare cannabinoid demonstrated neuroprotective effects in a population of affected neurons and promoted neurite outgrowth, signifying the potential to enhance neuronal function.

Two cannabinoid analogs identified to advance into in vivo studies in neurodegenerative disease

InMed has investigated several cannabinoids to understand and compare their effects in studies of neurodegenerative disease. Two cannabinoid analogs showing the most promising effects in neuroprotection and enhanced neuronal function have been selected to advance to in vivo studies in neurodegenerative disease.

Funding grant received and study to be conducted in collaboration with academia

InMed’s in vivo studies in neurodegenerative disease will be funded in part by a grant awarded to Dr. Ujendra Kumar of the faculty of Pharmaceuticals Sciences at UBC from the Natural Sciences and Engineering Research Council of Canada (NSERC), with InMed as the named industry partner. The funding will support the research and development studies of InMed’s cannabinoid pharmaceutical candidates, investigating their potential therapeutic effects in neurodegenerative diseases. The collaboration project is entitled “Pharmacological characterization of phytocannabinoids and the endocannabinoid system.”

International patent application filed for use of rare cannabinoid in treating neuronal disorders

InMed has filed an international patent application entitled “Compositions and Methods for Treating Neuronal Disorders with Cannabinoids” for use of a rare cannabinoid in the potential treatment of neurodegenerative diseases. This Patent Cooperation Treaty (PCT) application specifies a rare cannabinoid that may inhibit or slow the progression of neurodegenerative diseases by providing neuroprotection in a population of affected neurons. Furthermore, the PCT application also demonstrates the subject cannabinoid compound can also be used to promote neurite outgrowth, which signifies the potential to enhance neuronal function.

Cannabinoids and their potential role in neuronal disorders

Several published in vitro and in vivo studies have been conducted to understand the effects of different cannabinoids in neuronal disorders. There are a number of cannabinoid receptors or endocannabinoids, such as CB1, GPR6, GPR55 and 2-AG, that are expressed in the brain. Cannabinoids are highly lipophilic (dissolves in fats, oils and lipids) and can cross the blood brain barrier, making them potential pharmaceutical targets for neurodegenerative disease.

Rare cannabinoid pharmaceutical pipeline

Our therapeutic candidate for neurodegenerative disease is our third rare cannabinoid pharmaceutical development program. Our lead program, INM-755, is a cannabinol (CBN) cream in a Phase 2 clinical trial for epidermolysis bullosa. Our second program, INM-088, is a CBN eye drop formulation in preclinical studies investigating its potential as a treatment for glaucoma. Our neurodegenerative disease program applies a different rare cannabinoid from our lead program and has demonstrated neuronal effects in the potential treatment of neurodegenerative disease.


INM-755

A cannabinol (CBN) topical cream in Phase 2 clinical trials for epidermolysis bullosa
Learn More

IntegraSyn™

InMed’s flexible, integrated cannabinoid manufacturing system to efficiently produce pharmaceutical-grade, bio-identical cannabinoids.
Learn More
InMed-logo-mono
#310 – 815 West Hastings St.
Vancouver, BC, Canada
V6C 1B4

Pharmaceutical

  • Cannabinoids in Development
  • INM-755 for Epidermolysis Bullosa
  • INM-088 for Glaucoma
  • Neurodegenerative Disease
  • Novel Cannabinoid Analogs

MANUFACTURING

  • Cannabinoid Manufacturing Expertise
  • IntegraSyn™ Cannabinoid Manufacturing
  • BayMedica Cannabinoid Biosynthesis
  • Rare Cannabinoid Ingredients

Investor

  • News
  • Events
  • Stock Information
  • Corporate Governance
  • Financials & AGM
  • Filings
  • Presentations
  • Media

CORPORATE

  • Management
  • Board of Directors
  • Scientific Advisory Board
  • Partners and Collaborators
  • Events Calendar
  • Careers
  • Contact

Learn

  • What is Cannabinol (CBN)?
  • What is Epidermolysis Bullosa (EB)?
  • What is Glaucoma?
  • Cannabinoid Manufacturing Economics 101
  • GMP Manufacturing Standards by Product Type
  • Cannabinoids for Glaucoma
  • Cannabinoid Science
  • Articles and Videos

© Copyright 2023 InMed Pharmaceuticals Inc.

  • Privacy Policy
  • Terms of Use
  • Legal Disclaimer
  • Find Us On:
Subscribe

Sign up to receive emails from InMed Pharmaceuticals

Name*
Consent